18 thoughts on “NIACIN BIOMARKERS pt 1: Lists & Correlations: FORD BREWER”

  1. Human health status is very geeky to comprehensively understand, and very likely to get even geekier and more contradictory as more is realized and figured found out. It's gonna get real difficult to explain simply. I think you do an exceptionally fine job of explaining things to us, Dr Brewer, and hope you stick at it, you are literally saving life and needless suffering, and I for one thank you deeply. On a personal note I watched my comatose father take three weeks to die after a cerebral haemorhrage at 46, and his father died of a stroke in his 30's, so I've got a lot riding on countering CV inflammation, ( I take gram sized amounts of Vit C, plus do lots of other stuff) and pay a great deal of attention to what people who know what they're talking about say. Thank you again for all that you do.

  2. Based on the article- the punchline is Niacin brought down Trikes and raised HDL- but made insulin residents worse. Anyone can access the article.

    The study group- all high Trig low HDL- seems like they would have benefited from a LOw Carb Diet to bring down the trigs.

    It does prompt one to speculate that niacin with metaformin might work with a low carb diet- but that might be too obvious

  3. Hello Dr Brewer, I watched several of your videos a couple years ago, and lost track awhile, but just saw a couple today…wanted to say, your fogginess seems long gone, not sure what happened, but you are distinctly sharper. Well done! Keep up the whatever you are doing.

  4. While waiting on part two, I take 2 grams of nicotinic acid daily and have for a long time after a stint was installed years ago. Not as medical advice specific to me, but when the dust settles, so to speak, are you reconsidering your personal use of niacin? I believe you use the same brand as I do, being Rugby, but I don't use the timed release after some concerns from "SloNiacin" reported to contribute to liver problems. The timed release may be shorter duration than extended release, but I actually am now tolerant to flushing, so it's not a problem.

  5. Its nice to see more people looking into niacin. Did they make the difference between long release and short release niacins since they both have differences? Just curious. Anyway thumbs up 👍🏼.

  6. My doctor recently advised me to take 500 mg niacine twice daily, which I did. After about a week to 10 days, I noticed my resting heart rate was greatly elevated from normal, which felt terrible. I wondered if it were the niacin, so I went off it. After another week or so, the resting heart rate returned to normal. Am I intolerant to niacin or should I try a lower dose? My metabolic markers are good, but ldl-p is high. I want to reduce ldl-p, but don't want to mess up my insulin/glucose, etc. Hypothetically speaking, what would you advise a patient of yours about this?

  7. My husband was being tested for A-fib, and the cardiologist asked for a list of drugs and/or supplements he takes. He said to stop taking all of them, (these are vitamins such as K2 (mk7) and b complex and c etc.) and that Niacin increases your stroke risk, and that there is no proof that it does anything for anyone. I mentioned the cholesterol regulating, and he shot that down, too. I'm still taking my niacin, though. I think it's improved my mental clarity, short term memory, and my sleep is a bit better. But it's confusing, so many doctors saying so many different things.

  8. Question: Had a stent put in three months ago. Blood work numbers good. 5'7" 143 lb male, exercise… WHAT CAN I DO TO STABILIZE POTENTIAL HOT PLAQUE WITHOUT TAKING STATINS?

  9. My biggest concern with Niacin is the amount that I believe I heard you take exceeds the RDA by a substantial amount, and I've read, especially slow release can be hard on your liver, and kidneys, and can lead to concentrations of uric acid, gout, etc

  10. 1.5g non-extended-release niacin taken for 60 days increased HDL by 30% (up to 72) and decreased triglycerides by 30% (down to 100). But FBG went from 90 to 100; A1C from 4.9 to 5.3. LP(a) stayed the same (150 nmol). Trade-off worth it?

  11. as an aside on Niacin. 2019 Overview PubMed. "11. Conclusions

    A growing body of evidence highlights the key role of vitamin B3 in neuronal health. What is emerging is that niacin bioavailability is crucial for neuronsurvival and functions: indeed, vitamin deficiency has been recognized as a pathogenic factor for neurological deficits and dementia, as well as for neuronal injury and psychiatric disorders.

    Several molecular mechanisms are influenced by vitamin B3 (Figure 4), often strictly linked each other, thus making it difficult to define the precise mechanisms of action of this dietary metabolite. Although further research is needed, it may be speculated that optimal dietary intake of the vitamin will support neuronal health and delay neurodegeneration." https://www.mdpi.com/1422-0067/20/4/974/htm

  12. and also…2019 "In conclusion, our study demonstrates that higher niacin intake favorably modulates the effect of a lifestyle intervention on liver fat content. This suggests a beneficial effect of higher niacin consumption in reaching the therapeutic goals of a lifestyle intervention to improve hepatic steatosis. Intervention studies testing the influence of niacin-fortified foods on outcomes of a lifestyle intervention to treat NAFLD are now needed to validate this concept." https://www.nature.com/articles/s41598-018-38002-7

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